Structural basis of metallo-β-lactamase inhibition by captopril stereoisomers
β-Lactams are the most successful antibacterials, but their effectiveness is threatened by resistance, most importantly by production of serine- and metallo-β-lactamases (MBLs). MBLs are of increasing concern because they catalyse the hydrolysis of almost all β-lactam antibiotics, including recent g...
Những tác giả chính: | , , , , , , , , |
---|---|
Định dạng: | Journal article |
Được phát hành: |
American Society for Microbiology
2015
|