Structural basis for plexin activation and regulation
Class A plexins (PlxnAs) act as semaphorin receptors and control diverse aspects of nervous system development and plasticity, ranging from axon guidance and neuron migration to synaptic organization. PlxnA signaling requires cytoplasmic domain dimerization but extracellular regulation and activatio...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Published: |
Cell Press
2016
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