Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis--I. Biochemical and anatomical observations.

Unilateral ibotenic acid lesions of the rat nucleus basalis magnocellularis produce approximately 60% depletion of choline acetyltransferase activity in ipsilateral frontal and frontoparietal neocortex. This depletion, which represents the loss of most of the extrinsic neocortical cholinergic input,...

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Bibliographic Details
Main Authors: Fine, A, Dunnett, S, Björklund, A, Clarke, D, Iversen, S
Format: Journal article
Language:English
Published: 1985