Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis--I. Biochemical and anatomical observations.
Unilateral ibotenic acid lesions of the rat nucleus basalis magnocellularis produce approximately 60% depletion of choline acetyltransferase activity in ipsilateral frontal and frontoparietal neocortex. This depletion, which represents the loss of most of the extrinsic neocortical cholinergic input,...
Main Authors: | Fine, A, Dunnett, S, Björklund, A, Clarke, D, Iversen, S |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1985
|
Similar Items
-
Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis--II. Sensorimotor and learning impairments.
by: Dunnett, S, et al.
Published: (1985) -
Transplantation of embryonic ventral forebrain grafts to the neocortex of rats with bilateral lesions of nucleus basalis magnocellularis ameliorates a lesion-induced deficit in spatial memory.
by: Welner, SA, et al.
Published: (1988) -
Cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of Alzheimer disease.
by: Fine, A, et al.
Published: (1985) -
Impairment in T-maze reinforced alternation performance following nucleus basalis magnocellularis lesions in rats.
by: Salamone, J, et al.
Published: (1984) -
Place navigation in rats is impaired by lesions of medial septum and diagonal band but not nucleus basalis magnocellularis.
by: Hagan, J, et al.
Published: (1988)