The role of renal chloride channel mutations in kidney stone disease and nephrocalcinosis.

Recent advances in molecular biology have characterised a new class of chloride channels (CLCs) that are referred to as voltage-gated CLCs. To date nine such voltage-gated CLCs (CLC-1 to CLC-7, CLC-Ka and CLC-Kb, which are encoded by the genes CLCN1 to CLCN7, CLC-Ka and CLC-Kb, respectively) have be...

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Bibliographic Details
Main Author: Thakker, R
Format: Journal article
Language:English
Published: 1998