The risks and benefits of cyclo-oxygenase-2 inhibitors in prostate cancer: a review.

Cyclo-oxygenase (COX), also referred to as prostaglandin (PG) endoperoxidase synthase, is a key enzymatic mediator in the production of arachidonic acids to PGs and eicosanoids. Two isoforms of COX exist, namely COX-1 and COX-2, which have distinct physiological functions and tissue distribution. Ep...

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Bibliographic Details
Main Authors: Sooriakumaran, P, Kaba, R
Format: Journal article
Language:English
Published: 2005