Peptide nucleic acid probes with charged photocleavable mass markers: Towards PNA-based MALDI-TOF MS genetic analysis.

Halogen-labelled peptide organic acid (HPOA) monomers have been synthesised and incorporated into sequence-specific peptide nucleic acid (PNA) probes. Three different types of probe have been prepared; the unmodified PNA probe, the PNA probe with a mass marker, and the PNA probe with photocleavable...

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Detalhes bibliográficos
Principais autores: Ball, R, Green, P, Gale, N, Langley, G, Brown, T
Formato: Journal article
Idioma:English
Publicado em: 2010