Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes.

BACKGROUND: Predictive models of peptide-Major Histocompatibility Complex (MHC) binding affinity are important components of modern computational immunovaccinology. Here, we describe the development and deployment of a reliable peptide-binding prediction method for a previously poorly-characterized...

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Main Authors: Walshe, V, Hattotuwagama, C, Doytchinova, I, Wong, M, Macdonald, I, Mulder, A, Claas, F, Pellegrino, P, Turner, J, Williams, I, Turnbull, E, Borrow, P, Flower, DR
Format: Journal article
Language:English
Published: Public Library of Science 2009