Infectious tolerance and the long-term acceptance of transplanted tissue.

Short courses of antibody treatment aimed at blocking the coreceptors CD4 and CD8 and/or costimulatory molecules such as CD40L are able to bring about long-term acceptance and tolerance of allogeneic transplants. This tolerant state is operational, in that potential effector cells remain but are tig...

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Bibliographic Details
Main Authors: Waldmann, H, Adams, E, Fairchild, P, Cobbold, S
Format: Journal article
Language:English
Published: 2006