Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial.

BACKGROUND: Whether initial treatment for Parkinson's disease should consist of levodopa, dopamine agonists, or monoamine oxidase type B inhibitors (MAOBI) is uncertain. We aimed to establish which of these three classes of drug, as initial treatment, provides the most effective long-term contr...

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Bibliographic Details
Main Authors: Gray, R, Ives, N, Rick, C, Patel, S, Gray, A, Jenkinson, C, McIntosh, E, Wheatley, K, Williams, A, Clarke, C
Format: Journal article
Language:English
Published: Lancet 2014