Targeting β-catenin to inhibit the Wnt pathway in colorectal cancer cell lines

<p>In colorectal cancer (CRC), one of the post prevalent cancers, the Wnt signalling pathway is upregulated due to mutations in the key players <em>Adenomatous polyposis coli</em> (APC) and CTNNB1 (β-catenin). While intensive research efforts are being placed in blocking the Wnt pa...

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Bibliographic Details
Main Author: Colling, LA
Other Authors: Bodmer, W
Format: Thesis
Language:English
Published: 2019