Enhancement of humoral and cellular immunity with an anti-glucocorticoid-induced tumour necrosis factor receptor monoclonal antibody.

Adjuvants, including antibodies to tumour necrosis factor receptor superfamily members, augment immune responses. One member of this family, glucocorticoid-induced tumour necrosis factor receptor (GITR), is expressed at low levels on naive/resting T cells, B cells and macrophages, but at higher leve...

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Bibliographic Details
Main Authors: Ponte, J, Ponath, P, Gulati, R, Slavonic, M, Paglia, M, O'Shea, A, Tone, M, Waldmann, H, Vaickus, L, Rosenzweig, M
Format: Journal article
Language:English
Published: 2010