Multitasking roles of the mammalian deacetylase SIRT6
Sirtuins (SIRT) are highly conserved proteins first described as nicotinamide adenine dinucleotide (NAD+)-dependent type III histone deacetylases. They are the mammalian homologs of the SIR2 gene found in yeast. Seven homologs (SIRT1–7) have been described, all sharing an NAD+ binding catalytic doma...
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| Format: | Book section |
| Language: | English |
| Published: |
Academic Press
2018
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