Human MAIT cells show metabolic quiescence with rapid glucose-dependent upregulation of granzyme B upon stimulation

Mucosal-associated invariant T (MAIT) cells are a well-characterized innate-like T cell population abundant in the human liver, peripheral tissues and blood. MAIT cells serve in the first line of defense against infections, through engagement of their T cell receptor, which recognizes microbial meta...

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Detalles Bibliográficos
Autores principales: Zinser, ME, Highton, AJ, Kurioka, A, Kronsteiner, B, Hagel, J, Leng, T, Marchi, E, Phetsouphanh, C, Willberg, CB, Dunachie, SJ, Klenerman, P
Formato: Journal article
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018