Humanization of antibodies using a machine learning approach on large-scale repertoire data
<p><strong>Motivation:</strong> Monoclonal antibody therapeutics are often produced from non-human sources (typically murine), and can therefore generate immunogenic responses in humans. Humanization procedures aim to produce antibody therapeutics that do not elicit an immune respo...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2021
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