Functional architecture of pancreatic islets identifies a population of first responder cells that drive the first-phase calcium response
Insulin-secreting β-cells are functionally heterogeneous. Whether there exist cells driving the first-phase calcium response in individual islets, has not been examined. We examine “first responder” cells, defined by the earliest [Ca2+] response during first-phase [Ca2+] elevation, distinct from pre...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2022
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