Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein ib via AKT/glycogen synthase kinase-3/dynamin and integrin αiibβ3

<p style="text-align:justify;"> <b>Objective—</b> Platelet endothelial cell adhesion molecule-1 (PECAM-1) regulates platelet response to multiple agonists. How this immunoreceptor tyrosine-based inhibitory motif–containing receptor inhibits G protein-coupled receptor–med...

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Bibliographic Details
Main Authors: Jones, C, Sage, T, Moraes, L, Vaiyapuri, S, Hussain, U, Tucker, K, Barrett, N, Gibbins, J
Format: Journal article
Language:English
Published: American Heart Association 2014