Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells

<p style="text-align:justify;"> <b> Background:</b> Krüppel-like Factor 3 (KLF3) is a broadly expressed zinc-finger transcriptional repressor with diverse biological roles. During erythropoiesis, KLF3 acts as a feedback repressor of a set of genes that are activated by K...

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Main Authors: Funnell, A, Vernimmen, D, Lim, W, Mak, K, Wienert, B, Martyn, G, Artuz, C, Burdach, J, Quinlan, K, Higgs, D, Whitelaw, E, Pearson, R, Crossley, M
Format: Journal article
Language:English
Published: BioMed Central 2014