HIV escape and attenuation by cytotoxic T lymphocytes.

PURPOSE OF REVIEW: Much of the current HIV-1 vaccine research focuses on harnessing the cytotoxic T-lymphocyte arm of the immune response. However, HIV-1 appears to have an unerring ability to evade cytotoxic T-lymphocyte responses, through the process of escape mutation, and thus the potential ben...

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Bibliographic Details
Main Authors: Leslie, A, Goulder, P
Format: Journal article
Language:English
Published: 2006