The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice
The spontaneous destruction of insulin producing pancreatic beta cells in non-obese diabetic (NOD) mice provides a valuable model of type 1 diabetes. As in humans, disease susceptibility is controlled by the classical MHC class II genes that guide CD4+ T cell responses to self and foreign antigens....
| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
Public Library of Science
2013
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