Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.
Hypoxia-inducible factor (HIF)-1 is stabilized by hypoxia and iron chelation. We hypothesized that HIF-1 might be involved in pulmonary vascular regulation and that infusion of desferrioxamine over 8 h would consequently mimic hypoxia and elevate pulmonary vascular resistance. In study A, we charact...
Glavni autori: | Balanos, G, Dorrington, K, Robbins, P |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2002
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Slični predmeti
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Changes in pulmonary vascular resistance in humans during isocapnic hypoxia measured non-invasively using Doppler echocardiography
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Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans.
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