Bifunctional ligands for inhibition of tightbinding
The acknowledged potential of small-molecule therapeutics targeting disease-related protein-protein interactions (PPIs) has promoted active research in this field. The strategy of using small molecule inhibitors (SMIs) to fight strong (tight-binding) PPIs tends to fall short due to t...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Published: |
American Chemical Society
2016
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