Severe malaria is associated with parasite binding to endothelial protein C receptor.

Sequestration of Plasmodium falciparum-infected erythrocytes in host blood vessels is a key triggering event in the pathogenesis of severe childhood malaria, which is responsible for about one million deaths every year. Sequestration is mediated by specific interactions between members of the P. fal...

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Bibliographic Details
Main Authors: Turner, L, Lavstsen, T, Berger, S, Wang, C, Petersen, J, Avril, M, Brazier, A, Freeth, J, Jespersen, J, Nielsen, M, Magistrado, P, Lusingu, J, Smith, J, Higgins, M, Theander, T
Format: Journal article
Language:English
Published: 2013