Enhanced restoration of visual code after targeting ON bipolar cells compared to retinal ganglion cells with optogenetic therapy

Optogenetic therapy is a promising vision restoration method where light-sensitive opsins are introduced to the surviving inner retina following photoreceptor degeneration. The cell type targeted for opsin expression will likely influence the quality of restored vision. However, a like-for-like prec...

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Bibliographic Details
Main Authors: Rogers, J, Hughes, S, Ebrahimi, A, Allen, A, Storchi, R, Lindner, M, Peirson, S, Badea, T, Hankins, M, Lucas, R
Format: Journal article
Language:English
Published: Cell Press 2025