Route of monocyte differentiation determines their cytokine production profile: CD40 ligation induces interleukin 10 expression.
Interleukin 10 is a potent anti-inflammatory and immunomodulatory cytokine. Little is known regarding its induction in monocytes/macrophages, however LPS, a reproducible trigger of IL-10, is augmented by direct contact with T cells. In this context, the role of CD40-ligation is investigated. In the...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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