Genetic analysis of primaquine tolerance in a patient with relapsing vivax malaria.

Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide varia...

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Detalles Bibliográficos
Autores principales: Bright, A, Alenazi, T, Shokoples, S, Tarning, J, Paganotti, G, White, N, Houston, S, Winzeler, E, Yanow, S
Formato: Journal article
Lenguaje:English
Publicado: 2013