Genetic analysis of primaquine tolerance in a patient with relapsing vivax malaria.
Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide varia...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2013
|