Phase I trial of the SPf66 malaria vaccine in a malaria-experienced population in Southeast Asia.

In preparation for a recently reported, independent field trial of SPf66 malaria vaccine efficacy in Thailand, we first established the safety and immunogenicity of two clinical lots of U.S. manufactured lots of SPf66 in a series of overlapping Phase I studies. The vaccine was produced in approved l...

Full description

Bibliographic Details
Main Authors: Nosten, F, Luxemburger, C, Kyle, D, Gordon, D, Ballou, W, Sadoff, J, Brockman, A, Permpanich, B, Chongsuphajaisiddhi, T, Heppner, D
Format: Journal article
Language:English
Published: 1997