First atroposelective total synthesis of enantiomerically pure ancistrocladidine and ancistrotectorine

The first regio‐ and stereoselective total synthesis of the axially chiral 7,3′‐coupled naphthylisoquinoline alkaloids ancistrocladidine (1) and ancistrotectorine (2) has been described. Both possess a 7,3′‐coupled axis, which before now, was difficult to attain synthetically. Moreover, target 2 has...

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Bibliographic Details
Main Authors: Bringmann, G, Manchala, N, Büttner, T, Hertlein-Amslinger, B, Seupel, R
Format: Journal article
Language:English
Published: Wiley 2016