Molecular flexibility of DNA as a major determinant of RAD51 recruitment
<p>The timely activation of homologous recombination (HR) is essential for the maintenance of genome stability, in which the RAD51 recombinase plays a central role. <em>In vivo</em>, RAD51 polymerises on single-stranded DNA (ssDNA) at double-strand breaks (DSBs) to catalyse HR-dep...
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| Format: | Thesis |
| Language: | English |
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2018
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