Molecular flexibility of DNA as a major determinant of RAD51 recruitment

Molecular flexibility of DNA as a major determinant of RAD51 recruitment

<p>The timely activation of homologous recombination (HR) is essential for the maintenance of genome stability, in which the RAD51 recombinase plays a central role. <em>In vivo</em>, RAD51 polymerises on single-stranded DNA (ssDNA) at double-strand breaks (DSBs) to catalyse HR-dep...

Полное описание

Библиографические подробности
Главный автор:	Paoletti, F
Другие авторы:	Esashi, F
Формат:	Диссертация
Язык:	English
Опубликовано:	2018
Предметы:	Cancer research DNA repair > Mathematical models

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