DNA repair pathways as targets for cancer therapy.

DNA repair pathways can enable tumour cells to survive DNA damage that is induced by chemotherapeutic treatments; therefore, inhibitors of specific DNA repair pathways might prove efficacious when used in combination with DNA-damaging chemotherapeutic drugs. In addition, alterations in DNA repair pa...

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Autori principali: Helleday, T, Petermann, E, Lundin, C, Hodgson, B, Sharma, R
Natura: Journal article
Lingua:English
Pubblicazione: 2008