Structural basis for substrate specificity in human monomeric carbonyl reductases.

Carbonyl reduction constitutes a phase I reaction for many xenobiotics and is carried out in mammals mainly by members of two protein families, namely aldo-keto reductases and short-chain dehydrogenases/reductases. In addition to their capacity to reduce xenobiotics, several of the enzymes act on en...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Pilka, E, Niesen, F, Lee, W, El-Hawari, Y, Dunford, J, Kochan, G, Wsol, V, Martin, H, Maser, E, Oppermann, U
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2009
विषय:	methods chemistry Isoquinolines Humans Crystallography, X-Ray Cloning, Molecular Xenobiotics Substrate Specificity Kinetics Mutagenesis, Site-Directed Structure-Activity Relationship Alcohol Oxidoreductases Mutagenesis Ethanolamines pharmacology Temperature Antineoplastic Agents

Structural basis for substrate specificity in human monomeric carbonyl reductases. द्वारा Pilka, E, Niesen, F, Lee, W, El-Hawari, Y, Dunford, J, Kochan, G, Wsol, V, Martin, H, Maser, E, Oppermann, U

प्रकाशित 2009

Journal article

Structural basis for substrate specificity in human monomeric carbonyl reductases.

Structural basis for substrate specificity in human monomeric carbonyl reductases. द्वारा Pilka, E, Niesen, F, Lee, W, El-Hawari, Y, Dunford, J, Kochan, G, Wsol, V, Martin, H, Maser, E, Oppermann, U

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