Structural basis for substrate specificity in human monomeric carbonyl reductases.

Carbonyl reduction constitutes a phase I reaction for many xenobiotics and is carried out in mammals mainly by members of two protein families, namely aldo-keto reductases and short-chain dehydrogenases/reductases. In addition to their capacity to reduce xenobiotics, several of the enzymes act on en...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar:	Pilka, E, Niesen, F, Lee, W, El-Hawari, Y, Dunford, J, Kochan, G, Wsol, V, Martin, H, Maser, E, Oppermann, U
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2009
Konular:	methods chemistry Isoquinolines Humans Crystallography, X-Ray Cloning, Molecular Xenobiotics Substrate Specificity Kinetics Mutagenesis, Site-Directed Structure-Activity Relationship Alcohol Oxidoreductases Mutagenesis Ethanolamines pharmacology Temperature Antineoplastic Agents

Structural basis for substrate specificity in human monomeric carbonyl reductases. Yazar: Pilka, E, Niesen, F, Lee, W, El-Hawari, Y, Dunford, J, Kochan, G, Wsol, V, Martin, H, Maser, E, Oppermann, U

Baskı/Yayın Bilgisi 2009

Journal article

Structural basis for substrate specificity in human monomeric carbonyl reductases.

Structural basis for substrate specificity in human monomeric carbonyl reductases. Yazar: Pilka, E, Niesen, F, Lee, W, El-Hawari, Y, Dunford, J, Kochan, G, Wsol, V, Martin, H, Maser, E, Oppermann, U

Benzer Materyaller