Structural basis for antagonism of the ubiquitin ligase BIRC6 by SMAC
Apoptosis, a form of genetically programmed cell death, can be triggered by either internal or external signals ultimately activating caspases, a family of proteases1. Certain members of the inhibitors of apoptosis (IAP) family are sentinel proteins preventing untimely cell death by inhibiting caspa...
Main Authors: | Dietz, L, Ellison, CJ, Riechmann, C, Cassidy, CK, Felfoldi, FD, Pinto-Fernández, A, Kessler, BM, Elliott, PR |
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Format: | Internet publication |
Language: | English |
Published: |
2022
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