Sixty years of placebo-controlled antipsychotic drug trials in acute schizophrenia: Systematic review, Bayesian meta-analysis, and meta-regression of efficacy predictors.

<h4>Objective</h4> <p>Antipsychotic drug efficacy may have decreased over the decades. We, therefore, present a comprehensive meta-analysis of all placebo-controlled trials in acute schizophrenia, we investigate which trial characteristics have changed over the years and which one...

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Autori principali: Leucht, S, Leucht, C, Huhn, M, Chaimani, A, Mavridis, D, Helfer, B, Samara, M, Rabaioli, M, Bächer, S, Cipriani, A, Geddes, J, Salanti, G, Davis, J
Natura: Journal article
Lingua:English
Pubblicazione: American Psychiatric Association 2017