Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases.

The association of HLA-B27 with ankylosing spondylitis and reactive arthritis is the strongest one known between an MHC class I Ag and a disease. We have searched the proteome of the bacterium Chlamydia trachomatis for HLA-B27 binding peptides that are stimulatory for CD8(+) cells both in a model of...

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Bibliographic Details
Main Authors: Kuon, W, Holzhütter, H, Appel, H, Grolms, M, Kollnberger, S, Traeder, A, Henklein, P, Weiss, E, Thiel, A, Lauster, R, Bowness, P, Radbruch, A, Kloetzel, P, Sieper, J
Format: Journal article
Language:English
Published: 2001