Amine landscaping to maximize protein-dye fluorescence and ultrastable protein-ligand interaction
Chemical modification of proteins provides great opportunities to control and visualize living systems. The most common way to modify proteins is reaction of their abundant amines with N-hydroxysuccinimide (NHS) esters. Here we explore the impact of amine number and positioning on protein-conjugate...
Main Authors: | , , , |
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Format: | Journal article |
Published: |
Cell Press
2017
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