Accumulation of 111In-Labelled EGF-Au-PEG Nanoparticles in EGFR-Positive Tumours is Enhanced by Co-administration of Targeting Ligand

Accumulation of 111In-Labelled EGF-Au-PEG Nanoparticles in EGFR-Positive Tumours is Enhanced by Co-administration of Targeting Ligand

The successful use of targeted radionuclide therapy in the treatment of solid tumours may be limited by radioresistance, which necessitates delivery of a high dose of radioactivity. Nanoparticle (NP)-based delivery systems possess a large surface area for attachment of radioisotopes and so offer a s...

Podrobná bibliografie
Hlavní autoři:	Song, L, Able, S, johnson, E, Vallis, KA
Médium:	Journal article
Vydáno:	Ivyspring International Publisher 2017

Podobné jednotky

SPECT imaging and biodistribution studies of 111In-EGF-Au-PEG nanoparticles in vivo
Autor: Song, L, a další
Vydáno: (2016)

111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR.
Autor: Reilly, R, a další
Vydáno: (2000)

In-111-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR
Autor: Reilly, R, a další
Vydáno: (2000)

A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer.
Autor: Reilly, R, a další
Vydáno: (2000)

111In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells
Autor: Gill, M, a další
Vydáno: (2018)

Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells.
Autor: Chen, P, a další
Vydáno: (2002)

Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cytotoxicity, and tumor and normal-tissue uptake of [111In]DTPA-hEGF.
Autor: Hu, M, a další
Vydáno: (2007)

EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.
Autor: Song, L, a další
Vydáno: (2016)

An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells
Autor: Gill, MR, a další
Vydáno: (2020)

Indium-111 labeled leukocyte accumulation in extremity soft tissue sarcoma
Autor: Victor Fong, MD, a další
Vydáno: (2017-06-01)

EGF Functionalized Polymer-Coated Gold Nanoparticles Promote EGF Photostability and EGFR Internalization for Photothermal Therapy.
Autor: Catarina Oliveira Silva, a další
Vydáno: (2016-01-01)

Molecular radiotherapy using cleavable radioimmunoconjugates that target eGFR and γH2AX
Autor: Cornelissen, B, a další
Vydáno: (2013)

Presence of EGF ligand restricts the binding ability of EgB4 nanobody to EGFR extracellular domain
Autor: Duc Toan Truong, a další
Vydáno: (2025-01-01)

Relationship between induction of phosphorylated H2AX and survival in breast cancer cells exposed to 111In-DTPA-hEGF.
Autor: Cai, Z, a další
Vydáno: (2008)

Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and γH2AX.
Autor: Cornelissen, B, a další
Vydáno: (2013)

Amplified delivery of indium-111 to EGFR-positive human breast cancer cells.
Autor: Wang, J, a další
Vydáno: (2001)

On-Surface Synthesis of Ligands to Elaborate Coordination Polymers on an Au(111) Surface
Autor: Elie Geagea, a další
Vydáno: (2021-08-01)

Auger electron therapy using In-111-labelled F3 peptide
Autor: Cornelissen, B, a další
Vydáno: (2011)

Evidence that Argos is an antagonistic ligand of the EGF receptor.
Autor: Vinós, J, a další
Vydáno: (2000)

RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer
Autor: Marzia Di Donato, a další
Vydáno: (2023-10-01)

Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software.
Autor: Cai, Z, a další
Vydáno: (2009)

Tumours of the odontoid peg revisited
Autor: Ahmed Saad, a další
Vydáno: (2020-10-01)

Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation
Autor: Owen, J, a další
Vydáno: (2019)

Expression of EGF, EGFR, and proliferation in placentas from pregnancies complicated with preeclampsia
Autor: Indira Kosovic, a další
Vydáno: (2017-01-01)

Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation
Autor: Jianchao Zheng, a další
Vydáno: (2017-09-01)

HCC-derived EGFR mutants are functioning, EGF-dependent, and erlotinib-resistant
Autor: Natthaporn Sueangoen, a další
Vydáno: (2020-03-01)

The anti-tumor effect of the auger electron-emitting radiopharmaceutical, In-111-hEGF against MDA-MB-468 human breast cancer xenografts is tumor-size dependent.
Autor: Chen, P, a další
Vydáno: (2001)

Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using (111)In-bevacizumab.
Autor: Patel, N, a další
Vydáno: (2017)

Ligand exchange reactions and PEG stabilization of gold nanoparticles
Autor: Charitha Thambiliyagodage
Vydáno: (2022-01-01)

Biodistribution and imaging of an hsp90 ligand labelled with 111In and 67Ga for imaging of cell death
Autor: Ivan Ho Shon, a další
Vydáno: (2020-01-01)

Synthesis and evaluation of an 18F-labeled derivative of F3 for targeting surface expressed nucleolin in cancer and tumor endothelial cells
Autor: Vallis, K, a další
Vydáno: (2016)

Time-resolved proximity labeling of protein networks associated with ligand-activated EGFR
Autor: Mireia Perez Verdaguer, a další
Vydáno: (2022-06-01)

Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface
Autor: HaoRan Tang, a další
Vydáno: (2017-04-01)

USP25 Regulates EGFR Fate by Modulating EGF-Induced Ubiquitylation Dynamics
Autor: Carlos A. Niño, a další
Vydáno: (2020-11-01)

Deficiency of GABARAP but Not Its Paralogs Causes Enhanced EGF-Induced EGFR Degradation
Autor: Jochen Dobner, a další
Vydáno: (2020-05-01)

PKG II inhibits EGF/EGFR-induced migration of gastric cancer cells.
Autor: Lu Jiang, a další
Vydáno: (2013-01-01)

SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR.
Autor: J Terrig Thomas, a další
Vydáno: (2016-01-01)

Differential Expression Patterns of EGF, EGFR, and ERBB4 in Nasal Polyp Epithelium.
Autor: Chen Duan, a další
Vydáno: (2016-01-01)

Engineering Two-Dimensional Multilevel Supramolecular Assemblies from a Bifunctional Ligand on Au(111)
Autor: Rongyu Tang, a další
Vydáno: (2023-06-01)

A phase I trial of In-111-human epidermal growth factor in patients with metastatic EGFR-positive breast cancer
Autor: Vallis, K, a další
Vydáno: (2008)