An alkyne hydroacylation route to highly substituted furans.
More rings for your rhodium: Rhodium-catalyzed intermolecular alkyne hydroacylations deliver γ-hydroxy-α,β-enones, which can be cyclized in situ to deliver di-and trisubstituted furans. Functionalization of the intermediates using Heck chemistry allows the formation of regioisomeric furans. The use...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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