An alkyne hydroacylation route to highly substituted furans.

More rings for your rhodium: Rhodium-catalyzed intermolecular alkyne hydroacylations deliver γ-hydroxy-α,β-enones, which can be cyclized in situ to deliver di-and trisubstituted furans. Functionalization of the intermediates using Heck chemistry allows the formation of regioisomeric furans. The use...

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Detalhes bibliográficos
Main Authors: Lenden, P, Entwistle, D, Willis, M
Formato: Journal article
Idioma:English
Publicado em: 2011