TIMP-3, collagen, and elastin immunohistochemistry and histopathology of Sorsby's fundus dystrophy.

PURPOSE: Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP-3) gene have previously been identified in patients with Sorsby's fundus dystrophy (SFD). We evaluated the ocular distribution of TIMP-3 and other extracellular constituents in SFD. METHODS: The eyes of an SFD donor with a...

Full description

Bibliographic Details
Main Authors: Chong, N, Alexander, R, Gin, T, Bird, A, Luthert, P
Format: Journal article
Language:English
Published: 2000