Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival.

Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival.

Čájet eará veršuvnnaid (1)

Hypoxia and its down-stream activated pathways are commonly involved in tumor progression. Genes involved in angiogenesis and glycolysis, i.e. vascular endothelial growth factor (VEGF) and lactase dehydrogenase A (LDHA), respectively, are transcriptionally controlled by the hypoxia inducible factors...

Bibliográfalaš dieđut
Váldodahkkit:	Giatromanolaki, A, Sivridis, E, Bechrakis, N, Willerding, G, St Charitoudis, G, Foerster, M, Gatter, K, Harris, A, Koukourakis, M
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2012

Geahča maid

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Activated VEGFR2/KDR pathway in tumour cells and tumour associated vessels of colorectal cancer.
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Phosphorylated VEGFR-2 (pVEFGR-2/pKDR) is over-expressed in and translocates to the nucleus in acute leukemias: Analyses using a novel pKDR antibody.
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Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas.
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c-erbB-2 related aggressiveness in breast cancer is hypoxia inducible factor-1alpha dependent.
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Delivery of sodium morrhuate to hemangioma endothelial cells using immunoliposomes conjugated with anti-VEGFR2/KDR antibody
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The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer.
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Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival.
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CRISPR‐mediated knockout of VEGFR2/KDR inhibits cell growth in a squamous thyroid cancer cell line
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BNIP3 expression is linked with hypoxia-regulated protein expression and with poor prognosis in non-small cell lung cancer.
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Pyruvate Dehydrogenase and Pyruvate Dehydrogenase Kinase Expression in Non Small Cell Lung Cancer and Tumor-Associated Stroma
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