Substituted aryl benzylamines as potent and selective inhibitors of 17β-hydroxysteroid dehydrogenase type 3
17β-Hydroxysteroid dehydrogenase type 3 (17β-HSD3) is expressed at high levels in testes and seminal vesicles and is also present in prostate tissue and involved in gonadal and non-gonadal testosterone biosynthesis. The enzyme is membrane-bound and a crystal structure is not yet available. Selective...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
MDPI
2021
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