DNA duplexes stabilized by modified monomer residues: synthesis and stability
The synthesis of a series of 2′-deoxyuridine analogues modified at the 5-position and a series of 2′-deoxypurines modified at the 8-position is described. Ultraviolet melting studies have been used to assess the stability of DNA duplexes 12- and 8-residues in length that contain these modifications....
Main Authors: | , , |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
1998
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