DNA duplexes stabilized by modified monomer residues: synthesis and stability

DNA duplexes stabilized by modified monomer residues: synthesis and stability

The synthesis of a series of 2′-deoxyuridine analogues modified at the 5-position and a series of 2′-deoxypurines modified at the 8-position is described. Ultraviolet melting studies have been used to assess the stability of DNA duplexes 12- and 8-residues in length that contain these modifications....

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Dades bibliogràfiques
Autors principals:	Graham, D, Parkinson, J, Brown, T
Format:	Journal article
Idioma:	English
Publicat:	1998

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