DNA duplexes stabilized by modified monomer residues: synthesis and stability
The synthesis of a series of 2′-deoxyuridine analogues modified at the 5-position and a series of 2′-deoxypurines modified at the 8-position is described. Ultraviolet melting studies have been used to assess the stability of DNA duplexes 12- and 8-residues in length that contain these modifications....
Hlavní autoři: | , , |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
1998
|