DNA duplexes stabilized by modified monomer residues: synthesis and stability

The synthesis of a series of 2′-deoxyuridine analogues modified at the 5-position and a series of 2′-deoxypurines modified at the 8-position is described. Ultraviolet melting studies have been used to assess the stability of DNA duplexes 12- and 8-residues in length that contain these modifications....

Полное описание

Библиографические подробности
Главные авторы: Graham, D, Parkinson, J, Brown, T
Формат: Journal article
Язык:English
Опубликовано: 1998