Identification of antigen-specific B cell receptor sequences using public repertoire analysis.

High-throughput sequencing allows detailed study of the BCR repertoire postimmunization, but it remains unclear to what extent the de novo identification of Ag-specific sequences from the total BCR repertoire is possible. A conjugate vaccine containing Haemophilus influenzae type b (Hib) and group C...

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Bibliographic Details
Main Authors: Trück, J, Ramasamy, M, Galson, J, Rance, R, Parkhill, J, Lunter, G, Pollard, A, Kelly, D
Format: Journal article
Language:English
Published: American Association of Immunologists 2015