Neurokinin 3 receptor activation potentiates the psychomotor and nucleus accumbens dopamine response to cocaine, but not its place conditioning effects.

Neurokinin(3) receptors (NK(3)-Rs) have been implicated in psychomotor activity and reinforcement mechanisms. Recently, we showed that NK(3)-R antagonism blocked the psychostimulant properties of cocaine both in rats and in primates. Here, using in vivo microdialysis in the nucleus accumbens (NAc) o...

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Bibliographic Details
Main Authors: Jocham, G, Lauber, A, Müller, C, Huston, J, de Souza Silva, MA
Format: Journal article
Language:English
Published: 2007