Immunogenicity and protective efficacy of prime-boost regimens with recombinant (delta)ureC hly+ Mycobacterium bovis BCG and modified vaccinia virus ankara expressing M. tuberculosis antigen 85A against murine tuberculosis.

In the light of the recent emergence of multidrug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis, the epidemic of tuberculosis (TB) in populations coinfected with human immunodeficiency virus, and the failure of Mycobacterium bovis bacillus Calmette-Guerin (BCG) to pr...

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Bibliographic Details
Main Authors: Tchilian, E, Desel, C, Forbes, E, Bandermann, S, Sander, C, Hill, A, Mcshane, H, Kaufmann, S
Format: Journal article
Language:English
Published: 2009