A mathematical framework for developing freezing protocols in the cryopreservation of cells
When cooling cells to preserve them during cryopreservation, cooling too quickly results in the formation of lethal intracellular ice, while cooling too slowly amplifies the toxic effects of the cryoprotective agents (CPAs) added to slow down ice formation. We derive a mathematical model for cell cr...
Päätekijät: | , , , |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
Society for Industrial and Applied Mathematics
2020
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